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Gram-negative bacteria

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368

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-A0246A

    Bacterial Antibiotic Infection
    Flucloxacillin sodium is an active antibiotic against gram-positive and gram-negative bacteria .
    Flucloxacillin sodium
  • HY-W002677

    Antibiotic Bacterial Infection
    Fluoroquinolonic acid is a bacteriostatic antibiotic. Fluoroquinolonic acid has broad-spectrum activity against Gram-positive and Gram-negative bacteria .
    Fluoroquinolonic acid
  • HY-P10228

    Fungal Bacterial Infection
    S-Thanatin is an insect antimicrobial peptide with potent broad-spectrum antibacterial activity. S-Thanatin can inhibit the activity of Gram-negative bacteria, Gram-positive bacteria, and fungi, without cytotoxicity. The antibacterial activity of S-Thanatin is not affected by PH value, but monovalent cations (Na +/K +) can reduce its antibacterial activity against Gram-negative bacteria in a dose-dependent manner .
    S-Thanatin
  • HY-149309

    Topoisomerase Infection
    Topoisomerase inhibitor 2 (18C) is a bacterial topoisomeraseinhibitor that exhibits potent broad-spectrum activity against multidrug-resistant Gram-negative bacteria .
    Topoisomerase inhibitor 2
  • HY-122071

    Antibiotic Bacterial Infection
    Bicyclomycin is an antibiotic. Bicyclomycin has anti-Bacterial activity against Gram-negative bacteria except Proteus and Pseudomonas aeruginosa .
    Bicyclomycin
  • HY-P2794

    Bacterial Infection Neurological Disease Inflammation/Immunology
    G0775 is a molecule with potent, broad-spectrum activity against Gram-negative bacteria. G0775 is active against MDR bacteria. G0775 binds the LepB protease domain .
    G0775
  • HY-A0256
    Clavulanic acid
    4 Publications Verification

    Beta-lactamase Antibiotic Bacterial Infection Inflammation/Immunology
    Clavulanic acid is a naturally occurring powerful bacterial β-lactamases inhibitor for research of infections caused by bacteria, including infections of the ears. Clavulanic acid is active against a wide spectrum of gram-positive and gram-negative bacterias .
    Clavulanic acid
  • HY-D1697

    Fluorescent Dye Infection
    OGDA is a green fluorescent D-amino acid. OGDA is suitable for labeling peptidoglycan in Gram-positive and Gram-negative bacteria .
    OGDA
  • HY-B0734A

    SCE-963 hydrochloride

    Antibiotic Bacterial Infection
    Cefotiam (SCE-963) hydrochloride is a parenteral cephalosporin antibiotic. Cefotiam hydrochloride has broad-spectrum activity against Gram-positive and Gram-negative bacteria .
    Cefotiam hydrochloride
  • HY-B0734

    SCE-963

    Antibiotic Bacterial Infection
    Cefotiam (SCE-963) is a parenteral cephalosporin antibiotic. Cefotiam has broad-spectrum activity against Gram-positive and Gram-negative bacteria .
    Cefotiam
  • HY-B0734B

    SCE-963 dihydrochloride hydrate

    Antibiotic Bacterial Infection
    Cefotiam (SCE-963) dihydrochloride hydrate is a parenteral cephalosporin antibiotic. Cefotiam dihydrochloride hydrate has broad-spectrum activity against Gram-positive and Gram-negative bacteria .
    Cefotiam dihydrochloride hydrate
  • HY-114938

    Antibiotic Bacterial Infection
    Fumaramidmycin is an antibiotic found in Streptomyces kurssanovii NR-7GG1. Fumaramidmycin shows an antimicrobial activity against both Gram-positive and Gram-negative bacteria .
    Fumaramidmycin
  • HY-145440

    Bacterial Infection
    Colistin adjuvant-2 is a colistin adjuvant, shows increased colistin potentiation activity against Gram-negative bacteria .
    Colistin adjuvant-2
  • HY-145158

    Bacterial Antibiotic Infection
    Temocillin, a 6-alpha-methoxy penicillin derivative, is a semisynthetic beta-lactam antibiotic with a spectrum of activity against most aerobic Gram-negative bacteria .
    Temocillin
  • HY-N10097

    Na+/K+ ATPase Bacterial Infection
    Chamigrenol is a Na +/K +-ATPase inhibitor with an IC50 value of 15.9 μg/mL. Chamigrenol shows strong inhibitory activities against Gram-positive and Gram-negative bacteria except Escherichia coli, with MIC values of 50 µg/mL .
    Chamigrenol
  • HY-A0251

    Cefpodoxime acid; R 3763

    Antibiotic Bacterial Infection
    Cefpodoxime (Cefpodoxime acid) is a potent antibiotic active against gram-positive and gram-negative bacteria. Cefpodoxime inhibits the majority of cells in microbial populations. Cefpodoxime can be used for acute otitis media, sinusitis and tosillopharyngitis research .
    Cefpodoxime
  • HY-105180

    BO-2727 free acid

    Bacterial Infection
    Lenapenem (BO-2727 free acid), a carbapenem antibiotic, has potent antibacterial activity against Gram-positive and Gram-negative bacteria including P. aeruginosa .
    Lenapenem
  • HY-B1466

    BAY-f 1353 sodium

    Bacterial Antibiotic Infection
    Mezlocillin (BAY-f 1353) sodium is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin sodium is active against both gram-negative and gram-positive bacteria. Mezlocillin sodium can be used in bacterial infection research .
    Mezlocillin sodium
  • HY-116228

    Caderofloxacin; CS-940

    Bacterial Infection
    Cadrofloxacin (Caderofloxacin; CS-940), a orally active fluoroquinolone, is effective against aerobic/anaerobic Gram-positive and Gram-negative bacteria. Cadrofloxacin can be used for the research of infectious diseases .
    Cadrofloxacin
  • HY-136068

    Antibiotic Bacterial Autophagy Infection Cancer
    DCAP is a broad-spectrum antibiotic targeting the membranes of both Gram-positive and Gram-negative bacteria. DCAP blocks autophagy at the late stages by preventing autophagolysosome maturation and interrupting the autophagic flux .
    DCAP
  • HY-N0285S

    Ammidin-d6

    Isotope-Labeled Compounds Cholinesterase (ChE) HIV Bacterial Infection Neurological Disease
    Imperatorin-d6 (Ammidin-d6) is the deuterium labeled Imperatorin. Imperatorin is a BChE inhibitor and HIV-1 replication inhibitor. Imperatorin shows mild activity against Gram-negative bacteria .
    Imperatorin-d6
  • HY-P1630

    Bacterial Infection
    Buforin II, derived from buforin I, a protein isolated from the stomach of the Asian toad Bufo bufo gargarizans, is a potent antimicrobial peptide. Buforin II has antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria .
    Buforin II
  • HY-105049

    PPI-0903M

    Bacterial Infection
    T-91825 (PPI-0903M), an N-phosphono-type cephalosporin, is the active form of TAK-599. T-91825 is active against both gram-positive and gram-negative bacteria .
    T-91825
  • HY-P3914

    Oct-CA(1-7)M(2-9)

    Bacterial Infection
    Cecropin A (1-7)-Melittin A (2-9) is an antimicrobial peptide with antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria, as well as antimalarial activity, without the adverse hemolytic properties of bee venom peptides .
    Cecropin A (1-7)-Melittin A (2-9)
  • HY-N10271

    Bacterial Infection
    SCH 38519 is a platelet aggregation inhibitor. SCH 38519 inhibits thrombin-induced aggregation of human platelets with an IC50 of 68 μg/mL. SCH 38519 is also active against Gram-positive and Gram-negative bacteria .
    SCH 38519
  • HY-145439

    Bacterial NF-κB Infection
    Colistin adjuvant-1 is a colistin adjuvant, shows increased colistin potentiation activity against Gram-negative bacteria. Colistin adjuvant-1 inhibits NF-κB with an IC50 of 0.209 μM .
    Colistin adjuvant-1
  • HY-B0126

    Bacterial Antibiotic Infection
    Marbofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent, which has a broad spectrum bactericidal activity and good efficacy. Marbofloxacin can be used for the research of infections by Gram-positive and Gram-negative bacteria and Mycoplasma .
    Marbofloxacin
  • HY-B0126A

    Bacterial Antibiotic Infection
    Marbofloxacin hydrochloride is a third generation fluoroquinolone and orally active antimicrobial agent, which has a broad spectrum bactericidal activity and good efficacy. Marbofloxacin hydrochloride can be used for the research of infections by Gram-positive and Gram-negative bacteria and Mycoplasma .
    Marbofloxacin hydrochloride
  • HY-105048
    Omiganan
    1 Publications Verification

    Bacterial Antibiotic Infection
    Omiganan is a cationic antimicrobial peptide. Omiganan as an analogue of indolicidin shows activity against gram-positive and gram-negative bacteria but also Candida spp. isolates. Omiganan can be used for the research of alcohol nose and acne .
    Omiganan
  • HY-105033

    Pirfloxacin

    Bacterial Infection
    Irloxacin (Pirfloxacin) is a quinolone antibacterial agent. Irloxacin shows greater activity with an acid pH. Irloxacin has a good in vitro antimicrobial spectrum against both gram-positive and gram-negative bacteria. Orally active .
    Irloxacin
  • HY-133683

    3-Oxo-C14-AHL

    Others Metabolic Disease
    N-(3-Oxotetradecanoyl)-DL-homoserine lactone, a member of N-Acyl homoserine lactone (AHL) from gram-negative bacteria, is a quorum sensing (QS) signaling molecule .
    N-(3-Oxotetradecanoyl)-DL-homoserine lactone
  • HY-113678

    Polymyxin E

    Antibiotic Bacterial Infection
    Colistin (Polymyxin E) is an orally active polypeptide antibiotic. Colistin has excellent activity against various Gram-negative rod-shaped bacteria, including multidrug-resistant Pseudomonas aeruginosa, Acinetobacter baumannii and Klebsiella pneumoniae. Colistin is associated with nephrotoxicity. Colistin can be used for the research of infections caused by Gram-negative bacilli .
    Colistin
  • HY-P1631

    Bacterial Infection
    Polyphemusin I is a natural antimicrobial peptide with excellent antimicrobial activity against Gram-negative and Gram-positive bacteria. Polyphemusin I contains 18 amino acids and is stabilized into an amphiphilic, antiparallel β-hairpin by two disulfide bridges .
    Polyphemusin I
  • HY-B0136
    Cefdinir
    1 Publications Verification

    FK-482; CI-983

    Bacterial Antibiotic Infection
    Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin .
    Cefdinir
  • HY-155682

    Bacterial Infection
    Antibacterial agent 150 (compound 5g) is an antibacterial agent with potent antibacterial activity against both Gram-positive bacteria and Gram-negative bacteria (MIC values ranging from 1-32 μg/mL). Antibacterial agent 150 can increase survival rate of MRSA (Methicillin-resistant Staphylococcus aureus)-infected mice .
    Antibacterial agent 150
  • HY-B1802A
    Tosufloxacin tosylate hydrate
    2 Publications Verification

    A-61827 tosylate hydrate; T-3262

    Bacterial Antibiotic Infection
    Tosufloxacin tosylate hydrate (A-61827) is an orally active fluoroquinolone antibiotic. Tosufloxacin shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .
    Tosufloxacin tosylate hydrate
  • HY-B1802

    A-61827

    Antibiotic Bacterial Infection
    Tosufloxacin (A-61827) is an orally active fluoroquinolone antibiotic. Tosufloxacin shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .
    Tosufloxacin
  • HY-B1802C

    A-61827 tosylate

    Antibiotic Bacterial Infection
    Tosufloxacin (A-61827) tosylate is an orally active fluoroquinolone antibiotic. Tosufloxacin tosylate shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .
    Tosufloxacin tosylate
  • HY-B1210

    Bacterial Antibiotic Infection
    Pipemidic acid , a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid inhibits DNA gyrase. Pipemidic acid is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid can be used for the research of intestinal, urinary, and biliary tract infections .
    Pipemidic acid
  • HY-124679

    Bacterial Infection
    DS86760016 is a potent leucyl-tRNA synthetase (LeuRS) inhibitor with activity against multidrug-resistant (MDR) Gram-negative bacteria, such as Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa. DS86760016 inhibits LeuRS enzymes from Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii, with IC50s of 0.38, 0.62, and 0.16 μM, respectively .
    DS86760016
  • HY-138075

    Antibiotic Bacterial Infection
    Obafluorin is a β-Lactone Antibiotic, that can be produced by Pseudomonas fluorescens ATCC 39502. Obafluorin exhibits antibacterial activity against a range of Gram-positive and Gram-negative bacteria. Obafluorin fully inhibits E. coli threonyl-tRNA synthetase .
    Obafluorin
  • HY-163331

    Antibiotic Bacterial Infection
    Cresomycin is a bridged macrobicyclic antibiotic that can bind to the bacterial ribosome. Cresomycin exhibits efficacy against both Gram-positive and Gram-negative bacteria, including multidrug-resistant strains of Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa .
    Cresomycin
  • HY-A0089
    Colistin sulfate
    5+ Cited Publications

    Polymyxin E sulfate

    Bacterial Autophagy Antibiotic Infection
    Colistin sulfate is a polypeptide antibiotic which inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in the outer cell membrane of gram-negative bacteria.
    Colistin sulfate
  • HY-P3916

    Bacterial Infection Inflammation/Immunology
    GVLSNVIGYLKKLGTGALNAVLKQ is an antimicrobial peptide with 24-amino acid. GVLSNVIGYLKKLGTGALNAVLKQ can potentially form α-helix. GVLSNVIGYLKKLGTGALNAVLKQ (PGQ) has activity against Gram-negative, Gram-positive bacteria and the yeast Candida albicans .
    GVLSNVIGYLKKLGTGALNAVLKQ
  • HY-124712

    Bacterial Infection
    Divin, a potent chelator of iron, is a potent inhibitor of bacterial cell division with bacteriostatic effect in Gram-negative and Gram-positive bacteria. Divin disrupts the assembly of late division proteins, reduces peptidoglycan remodeling at the division site, and blocks compartmentalization of the cytoplasm .
    Divin
  • HY-139010

    CI-934

    SARS-CoV Infection
    Merafloxacin (CI-934), a fluoroquinolone antibacterial agent, is a selective programmed -1 ribosomal frameshifting (-1 PRF) inhibitor of beta coronaviruses. Merafloxacin exhibits in vitro activity against gram-positive and gram-negative bacteria .
    Merafloxacin
  • HY-N3138

    Bacterial Infection
    Ombuoside is a glycoside ombuoside isolated from Gynostemma pentaphyllum.Ombuoside has antimicrobial activity against several strains of gram-positive and gram-negative bacteria and the yeast Candida albicans . Ombuoside has antioxidant effects by scavenging free radicals and ROS .
    Ombuoside
  • HY-B0200
    Cephalexin
    5+ Cited Publications

    Cefalexin; Cephacillin

    Penicillin-binding protein (PBP) Antibiotic Bacterial Infection Cancer
    Cephalexin (Cefalexin) is a potent, orally active semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum. Cephalexin has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. Cephalexin is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al .
    Cephalexin
  • HY-B0159

    Q-35

    Bacterial Antibiotic Infection
    Balofloxacin (Q-35) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin can be used for the research of respiratory, intestinal, and urinary tract infections .
    Balofloxacin
  • HY-B1085
    Cinoxacin
    1 Publications Verification

    Compound 64716

    Bacterial Antibiotic DNA/RNA Synthesis Infection
    Cinoxacin (Compound 64716), a synthetic antimicrobial related to the quinolone class of orally active antibacterial agent. Cinoxacin has antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. Cinoxacin can be used for the research of urinary tract infections and bacterial prostatitis .
    Cinoxacin

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